Towards design strategies for anion–π interactions in crystal engineering

Towards design strategies for anion–π interactions in crystal engineering

Crystal Engineering for Product and Process Design

Crystalline organic solids are ubiquitous as either final products or as intermediates in the specialty chemical, pharmaceutical, and home & personal care industries. Virtually all small molecular weight drugs are isolated as crystalline materials, and over 90% of all pharmaceutical products are formulated in particulate, generally crystalline form. Crystalline chemical intermediates, such as a...

Data mining for decision making in engineering optimal design

Often in modeling the engineering optimization design problems, the value of objective function(s) is not clearly defined in terms of design variables. Instead it is obtained by some numerical analysis such as FE structural analysis, fluid mechanic analysis, and thermodynamic analysis, etc. Yet, the numerical analyses are considerably time consuming to obtain the final value of objective functi...

Towards reliability-based design for geotechnical engineering

This paper presents an overview of the evolution in structural and geotechnical design practice over the past half a decade or so in relation to how uncertainties are dealt with. For the general reader who is encountering reliability-based design (RBD) for the first time, this would provide a valuable historical perspective of our present status and important outstanding issues that remain to b...

Trade - Off Strategies in Engineering Design ∗

A formal method to allow designers to explicitly make trade-off decisions is presented. The methodology can be used when an engineer wishes to rate the design by the weakest aspect, or by cooperatively considering the overall performance, or a combination of these strategies. The design problem is formulated with preference rankings, similar to a utility theory or fuzzy sets approach. This appr...